Bupropion is widely used for treating bipolar disorder BD , and especially those with depressive mood, based on its good treatment effect, safety profile, and lower risk of phase shifting. However, increasing evidence indicates that the safety of bupropion in BD patients may not be as good as previously thought. The aim of this study was to summarize data on the treatment effect and safety profile of bupropion in the treatment of BD via a meta-analysis. The inclusion criteria were: i studies comparing changes in disease severity before and after bupropion treatment or articles comparing the treatment effect of bupropion in BD patients with those receiving other standard treatments; ii articles on clinical trials in humans. All effect sizes from 10 clinical trials were pooled using a random effects model. We examined the possible confounding variables using meta-regression and subgroup analysis.
A Pill’s Surprises, for Patient and Doctor Alike
Bupropion is a prescription drug. It comes in the form of an immediate-release tablet or an extended-release tablet. Both forms are taken by mouth. An extended-release drug is released into your system slowly over time. An immediate-release drug works more quickly. Generic drugs usually cost less than the brand-name version.
interested readers anywhere in the world to learn about and keep up to date with Jefferson caution in anyone who is at increased risk ofseizures or who has a.
Learn More. Or in a crisis , text “NAMI” to Donate Now. All FDA black box warnings are at the end of this fact sheet. Please review before taking this medication. Bupropion is an antidepressant medication that works in the brain. It is approved for the treatment of major depressive disorder MDD , seasonal affective disorder SAD , and to help people quit smoking smoking cessation. SAD is a type of depression that occurs mainly during the autumn-winter season.
Would You Date Someone Who Takes Antidepressants?
We’re committed to providing you with the very best cancer care, and your safety continues to be a top priority. This is just one more way of ensuring your safety and that of our staff. Read more. Tell your doctor and pharmacist about all of your drugs prescription or OTC, natural products, vitamins and health problems.
After three weeks of dating someone, he saw me take my meds, Wellbutrin, in the morning—two pills from two separate bottles. The bathroom.
Taking antidepressants may affect people’s feelings of love and attachment, a new study suggests. Researchers found that men’s feelings of love tended to be affected more than women’s by taking antidepressants called selective serotonin reuptake inhibitors SSRIs , which work mainly through the serotonin system. In contrast, drugs called tricyclic antidepressants, which affect the serotonin system less, seem to affect women’s feelings of love more than men’s, the researchers said.
Hagop S. Akiskal, a distinguished professor of psychiatry at the University of California, San Diego. In the study, researchers compared the effects of SSRIs and tricyclic antidepressants on the love lives of people with depression — women and 69 men — whose mean age was The study included 13 people who were homosexual. All the people in the study said they had been in loving relationships for between seven months and 26 years.
The participants filled out a questionnaire that examined their feelings of love, attachment and sexual attraction to their partners throughout their relationships. On the questionnaire, the participants addressed whether their feelings were different after they started taking antidepressants, compared with before. When the researchers looked at all the study participants, they found that those taking SSRIs were more likely to say they felt less at ease with sharing their partners’ thoughts and feelings, and less wishful that their love for their partner would last forever since they started taking their medication, compared with the people taking tricyclics.
They also found the men in the study taking SSRIs reported being less likely to ask their partners for help or advice, or take care of their partners, compared with women who had been taking SSRIs.
Where Is the Love? Antidepressants May Inadvertently Blunt Feelings of Romance
Bupropion is an antidepressant used to treat major depressive disorder and seasonal affective disorder. The Zyban brand of bupropion is used to help people stop smoking by reducing cravings and other withdrawal effects. Bupropion may also be used for purposes not listed in this medication guide.
This risk is higher if you or anyone in your family has or has ever had bipolar disorder or mania or has thought about or attempted suicide. Talk to your doctor.
Study record managers: refer to the Data Element Definitions if submitting registration or results information. Female orgasmic disorder is characterized by a recurrent or persistent difficulty in achieving orgasm during sexual activity. Epidemiological studies in Sweden and the United Kingdom have found similar rates of orgasm disorder. Studies of drugs with actions of increasing genital vasodilation in response to sexual stimulation eg alprostadil, sildenafil, or phentolamine have generally been found to be unsuccessful or to have extremely limited efficacy in reversing female sexual dysfunction Basson, ; Segraves, There have been fewer studies of pharmacological treatment for hypoactive sexual desire disorder in premenopausal women.
In addition one controlled study Crenshaw et al, and several clinical series indicate that bupropion may have prosexual effects in non-depressed females Modell et al, A single blind study Segraves et al, found that bupropion increased the frequency of episodes of sexual arousal and desire for sexual activity in women diagnosed with hypoactive sexual desire disorder.
A recent multicenter, double-blind, fixed dose study of females with global, acquired hypoactive sexual desire disorder found evidence that an exposure to to mg bupropion XL increased orgasm and pleasure as measured by the CSFQ-F. In this pilot study, all women had total serum testosterone levels within normal limits and were in stable, non-conflictual relationships.
All patients had no evidence of psychiatric disorder and no evident etiology to their sexual complaint.
Medically reviewed by Drugs. Wellbutrin XL is an antidepressant used to treat major depressive disorder and seasonal affective disorder. The Zyban brand of bupropion is used to help people stop smoking by reducing cravings and other withdrawal effects. You should not take Wellbutrin XL if you have seizures or an eating disorder, or if you have suddenly stopped using alcohol, seizure medication, or sedatives.
If you take Wellbutrin for depression, do not also take Zyban to quit smoking. Do not use Wellbutrin XL within 14 days before or 14 days after you have used an MAO inhibitor , such as isocarboxazid , linezolid , methylene blue injection, phenelzine , rasagiline , selegiline , or tranylcypromine.
Official Title: A Multi-center, Double-blind, Placebo-controlled Study of Bupropion XL in Females With Orgasmic Disorder. Study Start Date.
Jump to navigation. We reviewed the evidence on the effects of the drug bupropion in adults with ADHD. We also reviewed adverse effects side effects experienced as a result of taking the drug. Some people with ADHD only have problems with one of the behaviors, while others have a combination. Bupropion is a drug that is registered for the treatment of depression and for stopping smoking, but is also used to treat ADHD.
People with ADHD are usually prescribed stimulant drugs such as methylphenidate and amphetamines. However, not everyone responds well to stimulants.
Bupropion Reduces Methamphetamine-Induced Subjective Effects and Cue-Induced Craving
Medically reviewed by Sanjai Sinha, MD. Last updated on Mar 3, Bupropion is an antidepressant medication used to treat major depressive disorder and seasonal affective disorder. The Zyban brand of bupropion is used to help people stop smoking by reducing cravings and other withdrawal effects.
Drug information provided by: IBM Micromedex. Bupropion is used to treat depression and to prevent depression in patients with seasonal affective disorder SAD , which is sometimes called winter depression. It is also used as part of a support program to help people stop smoking. Bupropion is sold under different brand names.
If you are already taking medicine for depression or to help you stop smoking, discuss this with your doctor before taking bupropion. It is very important that you receive only one prescription at a time for bupropion. In deciding to use a medicine, the risks of taking the medicine must be weighed against the good it will do. This is a decision you and your doctor will make. For this medicine, the following should be considered:. Tell your doctor if you have ever had any unusual or allergic reaction to this medicine or any other medicines.
Bupropion (Zyban) for Quitting Smoking
You are viewing BNF. Acute alcohol withdrawal ; acute benzodiazepine withdrawal ; bipolar disorder ; CNS tumour ; eating disorders ; history of seizures ; severe hepatic cirrhosis. Alcohol abuse ; diabetes ; elderly ; history of head trauma ; predisposition to seizures prescribe only if benefit clearly outweighs risk. Abdominal pain ; anxiety ; concentration impaired ; constipation ; dizziness ; dry mouth ; fever ; gastrointestinal disorder ; headache ; hyperhidrosis ; hypersensitivity ; insomnia reduced by avoiding dose at bedtime ; nausea ; skin reactions ; taste altered ; tremor ; vomiting.
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The problem here is bupropion (brand name Wellbutrin), the well-known antidepressant. The FDA considers the generic form of bupropion XL mg (Teva to happen is for someone in the Agency to be held accountable for this. a date when we will update the information posted on the website”.
There are data to support the use of certain antidepressants during pregnancy. Most of the research over the last decade has focused on the selective serotonin reuptake inhibitors SSRIs like fluoxetine Prozac and the older tricyclic antidepressants, but there is some new data supporting the use of bupropion during pregnancy. The most recent information from the Bupropion Pregnancy Registry maintained by the manufacturer GlaxoSmithKline includes data from pregnancies involving first trimester exposure to bupropion.
In this sample, there were 20 infants with major malformations. This represents a 3. Health care providers may receive an updated report from GlaxoSmithKline by calling While this information regarding the overall risk of malformation is reassuring, earlier reports had revealed an unexpectedly high number of malformations of the heart and great vessels in bupropion-exposed infants.
To more carefully quantify the risk for cardiovascular malformation in bupropion-exposed infants, another study was conducted relying upon two large insurance claims databases Cole et al, Outcomes were compared in three different groups: 1 women dispensed bupropion during the first trimester, 2 women dispensed other antidepressant during the first trimester, and 3 women dispensed bupropion after the first trimester. This retrospective cohort study including over infants exposed to bupropion during the first trimester did not reveal an increased risk of malformations in the bupropion-exposed group of infants nor did it demonstrate an increased risk for cardiovascular malformations.